Conference program – to be announced
Invited Speakers
Beyond Recognition: N-Glycosylation-driven strategies to enhance efficacy of CAR-T cell based immunotherapies
Agnieszka Graczyk-Jarzynka, PhD
Mossakowski Medical Research Institute Polish Academy of Sciences
Dr. Graczyk-Jarzynka is an Assistant Professor in the Department of Immunology at the Mossakowski Medical Research Institute of the Polish Academy of Sciences (PAS). She earned her doctorate in biological sciences in 2014 at the Nencki Institute of Experimental Biology PAS and completed postdoctoral training at the Medical University of Warsaw. She specializes in immunotherapy and genetic engineering. Her field of expertise include constructing chimeric antigen receptors (CARs) de novo and developing CAR-T cell therapies targeting novel antigens with a focus on solid tumor immunotherapy. Her research explores how tumor cells and T cells change during antitumor response and investigates surfaceome and N-glycome remodeling of, both, tumor cells and T cells, as potential therapeutic enhancers of immunotherapy
Insights into the evolution of the mammalian brain via comparative
N-glycomics
Thomas Klarić, PhD
Genos d.o.o., Zagreb, CroatiaPhD
Dr. Thomas Klarić seeks to combine his interests in neuroscience and glycobiology to address questions of fundamental importance at the interface of these two fields. He graduated from the University of Adelaide with a Bachelor of Biotechnology (Honours) in 2005 and obtained a PhD from the School of Molecular and Biomedical Science at the same institution in 2012. Between 2012 and 2014 he was employed as a postdoctoral researcher in the University of Adelaide Stroke Research Programme where he used rodent models of stroke to investigate the effectiveness of stem cell therapy as a treatment option. In 2014 he was awarded a NewFelPro postdoctoral fellowship as part of the FP7 Marie Skłodowska-Curie Actions initiative to work in Genos Ltd. on the Human Neuroglycome Project where he investigated the spatiotemporal profile of N-glycosylation in the human brain using liquid chromatography and mass spectrometry. In 2018 he received a Fulbright fellowship to undertake postdoctoral training at the Yale University School of Medicine where his research focused on transcriptional control of mouse neurodevelopment. As of April 2020, he is once again in Genos Ltd. where he is applying his expertise in glycan analysis to investigate key research questions at the cutting edge of neuroglycobiology.
